Live Attenuated Vaccines has 13 known drug interactions based on U.S. FDA drug labeling data. Of these, 2 are contraindicated combinations that should be avoided entirely. 6 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Amantadine Hydrochloride, Fingolimod, Amantadine. Patients taking Live Attenuated Vaccines should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 13
- Contraindicated
- 2
- Major
- 6
- Moderate
- 5
Contraindicated (2)
- Live Attenuated Vaccines + Amantadine Hydrochloride— Should not be administered within 2 weeks before or 48 hours after amantadine hydrochloride due to potential interferenc…
- Live Attenuated Vaccines + Fingolimod— Avoid live attenuated vaccines during and for 2 months after fingolimod treatment due to risk of infection from immunosu…
Major (6)
- Live Attenuated Vaccines + Amantadine— Amantadine's antiviral properties may interfere with vaccine efficacy. Live vaccines are not recommended during treatmen…
- Live Attenuated Vaccines + Fingolimod Lauryl Sulfate— Avoid during and for 2 months after TASCENSO ODT treatment due to risk of infection from reduced immune response.
- Live Attenuated Vaccines + Oseltamivir Phosphate— Oseltamivir may inhibit replication of live vaccine virus and reduce LAIV efficacy. Avoid LAIV administration within 2 w…
- Live Attenuated Vaccines + Ponesimod— Live attenuated vaccines should be avoided during and for 1-2 weeks after PONVORY treatment due to risk of infection.
- Live Attenuated Vaccines + Prednisolone Sodium Phosphate— Corticosteroids may potentiate replication of organisms in live attenuated vaccines and suppress antibody response; rout…
- Live Attenuated Vaccines + Siponimod— Avoid live-attenuated vaccines during and for up to 4 weeks after treatment with siponimod due to immunosuppressive effe…
Moderate (5)
- Live Attenuated Vaccines + Baloxavir Marboxil— Concurrent administration of antiviral drugs may inhibit viral replication of LAIV and thereby decrease the effectivenes…
- Live Attenuated Vaccines + Oseltamivir— Oseltamivir may inhibit replication of live vaccine virus and reduce efficacy of LAIV. Avoid LAIV administration within …
- Live Attenuated Vaccines + Peramivir— Antiviral drugs may inhibit viral replication and reduce vaccine efficacy. Avoid use of LAIV within 2 weeks before or 48…
- Live Attenuated Vaccines + Rimantadine Hydrochloride— Potential interference between products. LAIV should not be administered until 48 hours after rimantadine cessation; rim…
- Live Attenuated Vaccines + Zanamivir— LAIV should not be administered within 2 weeks before or 48 hours after RELENZA administration due to potential interfer…