Does Abacavir Lamivudine And Zidovudine Interact with Interferon Alfa?
CDI records a major classification for Abacavir Lamivudine And Zidovudine and Interferon Alfa. The stored summary is: Coadministration may increase hematologic toxicity of zidovudine. The mechanism involves bone marrow suppression. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Major
- Abacavir Lamivudine And Zidovudine Class
- Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor
- Management
- Close medical supervision required
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Bone marrow suppression
What To Tell Your Doctor or Pharmacist
If you are taking Abacavir Lamivudine And Zidovudine and your doctor is considering prescribing Interferon Alfa (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask how frequently you should be monitored while these are co-prescribed
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider