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Does Adrenergic Blockers Interact with Anakinra?

Adrenergic Blockers and Anakinra have a major drug interaction according to U.S. FDA drug labeling data. Use of KINERET in combination with TNF blocking agents is not recommended due to increased serious infections. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Major
Anakinra Class
Interleukin-1 Receptor Antagonist
Management
Close medical supervision required
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Adrenergic Blockers and your doctor is considering prescribing Anakinra (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask how frequently you should be monitored while these are co-prescribed
  • Ask whether any dosage adjustments are needed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Adrenergic Blockers+💊 Anakinra(Kineret)

Severity & Interaction Details

⚠️
major
Use with caution — major interaction
Serious risk of clinically significant harm. Generally avoid; if used, monitor closely.
Severity scale
MinorContra
On record
Yes
Drug A class
—
Drug B class
Interleukin-1 Receptor Antagonist
Source
NLP:anakinra

What this means in plain English

Use of KINERET in combination with TNF blocking agents is not recommended due to increased serious infections.

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Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.