Home›Infliximab Axxq›Infliximab Axxq + Anakinra

Does Infliximab Axxq Interact with Anakinra?

Infliximab Axxq and Anakinra have a contraindicated drug interaction according to U.S. FDA drug labeling data. Combination with TNF blockers increased risk of serious infections with no added clinical benefit. Not recommended due to similar toxicities with TNF blocker therapy. The mechanism involves increased immunosuppression and serious infections. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Contraindicated
Infliximab Axxq Class
Tumor Necrosis Factor Blocker
Anakinra Class
Interleukin-1 Receptor Antagonist
Management
Do not take together
Data Source
U.S. FDA via OpenFDA

How This Interaction Works

The interaction between Infliximab Axxq and Anakinra occurs because increased immunosuppression and serious infections. Clinically, this means combination with tnf blockers increased risk of serious infections with no added clinical benefit. not recommended due to similar toxicities with tnf blocker therapy. Because of the severity of this interaction, these medications are contraindicated — meaning they should not be taken together under any circumstances. If you are currently taking both, contact your healthcare provider immediately to discuss alternatives.

What To Tell Your Doctor or Pharmacist

If you are taking Infliximab Axxq and your doctor is considering prescribing Anakinra (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask about alternative medications that do not interact with your current regimen
  • Ask how frequently you should be monitored while these are co-prescribed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Infliximab Axxq(Avsola)+💊 Anakinra(Kineret)

Severity & Interaction Details

⛔
contraindicated
Avoid this combination
FDA labeling lists this pair as contraindicated. The risk outweighs the benefit in nearly all cases.
Severity scale
MinorContra
On record
Yes
Drug A class
Tumor Necrosis Factor Blocker
Drug B class
Interleukin-1 Receptor Antagonist
Source
NLP:infliximab-axxq

What this means in plain English

Combination with TNF blockers increased risk of serious infections with no added clinical benefit. Not recommended due to similar toxicities with TNF blocker therapy.

What the FDA label says

"Increased immunosuppression and serious infections"

📖 Source: NLP:infliximab-axxq

Share this result:XFacebookWhatsAppReddit
Add more drugs
Check Infliximab Axxq and Anakinra against your full medication list

Most patients take more than two medications. CDI checks every pair across up to 20 drugs simultaneously — including OTCs and common supplements.

Add more drugs →

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.