Does Androgen Deprivation Therapeutic Drugs Interact with Cefdinir?
Androgen Deprivation Therapeutic Drugs and Cefdinir have a moderate drug interaction according to U.S. FDA drug labeling data. Concomitant administration reduces extent of cefdinir absorption by approximately 80%. Should be taken at least 2 hours before or after iron supplement. Forms nonabsorbable complex in GI tract. The mechanism involves formation of nonabsorbable complex between cefdinir and iron in gastrointestinal tract. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Cefdinir Class
- Cephalosporin Antibacterial
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Androgen Deprivation Therapeutic Drugs and Cefdinir occurs because formation of nonabsorbable complex between cefdinir and iron in gastrointestinal tract. Clinically, this means concomitant administration reduces extent of cefdinir absorption by approximately 80%. should be taken at least 2 hours before or after iron supplement. forms nonabsorbable complex in gi tract. This is classified as a moderate interaction. While it may not require stopping either medication, your healthcare provider should be aware you are taking both so they can monitor for potential effects and adjust treatment if necessary.
What To Tell Your Doctor or Pharmacist
If you are taking Androgen Deprivation Therapeutic Drugs and your doctor is considering prescribing Cefdinir (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider