Does Angiotensin Ii Interact with Potassium Chloride Extended Release?
CDI records a major classification for Angiotensin Ii and Potassium Chloride Extended Release. The stored summary is: ACE inhibitors may increase serum potassium levels when used with potassium chloride, potentially leading to hyperkalemia. The mechanism involves reduced urinary potassium excretion. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Major
- Angiotensin Ii Class
- Vasoconstrictor
- Management
- Close medical supervision required
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Reduced urinary potassium excretion
What To Tell Your Doctor or Pharmacist
If you are taking Angiotensin Ii and your doctor is considering prescribing Potassium Chloride Extended Release (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask how frequently you should be monitored while these are co-prescribed
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider