Does Angiotensin Ii Interact with Triamterene And Hydrochlorothiazide?
CDI records a major classification for Angiotensin Ii and Triamterene And Hydrochlorothiazide. The stored summary is: Greatly increased risk of hyperkalemia when potassium-sparing agents are used with ACE inhibitors. Serum potassium should be monitored frequently. The mechanism involves increased potassium retention leading to hyperkalemia. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Major
- Angiotensin Ii Class
- Vasoconstrictor
- Triamterene And Hydrochlorothiazide Class
- Thiazide Diuretic
- Management
- Close medical supervision required
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Increased potassium retention leading to hyperkalemia
What To Tell Your Doctor or Pharmacist
If you are taking Angiotensin Ii and your doctor is considering prescribing Triamterene And Hydrochlorothiazide (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask how frequently you should be monitored while these are co-prescribed
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider