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Does Apixaban Interact with Ibuprofen?

No documented interaction between Apixaban and Ibuprofen was found in our FDA drug labeling database. This does not guarantee the combination is safe for every patient — drug interaction databases are updated periodically as new information becomes available. Always consult your pharmacist or physician before combining medications. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
None
Apixaban Class
Factor Xa Inhibitor
Ibuprofen Class
Nonsteroidal Anti-inflammatory Drug
Management
Consult your pharmacist
Data Source
U.S. FDA via OpenFDA
💊 Apixaban(Eliquis)+💊 Ibuprofen(Ibu)

Severity & Interaction Details

✅
none
No interaction documented
We found no documented interaction between these two drugs in the FDA labeling data.
Severity scale
MinorContra
On record
Not found
Drug A class
Factor Xa Inhibitor
Drug B class
Nonsteroidal Anti-inflammatory Drug
Source
—

✅ No documented interaction in our FDA-label dataset.

This means no interaction between Apixaban and Ibuprofen was surfaced from openFDA or NIH NLM sources. It does not guarantee the combination is safe for every patient — always confirm with your pharmacist.

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.