Does Ascorbic Acid Interact with Fluphenazine?
CDI records a moderate classification for Ascorbic Acid and Fluphenazine. The stored summary is: Concurrent administration of ascorbic acid and fluphenazine may result in decreased fluphenazine plasma concentrations. Standard monitoring is warranted. The mechanism involves urine acidification alters excretion. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Ascorbic Acid Class
- Vitamin C
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Urine acidification alters excretion
What To Tell Your Doctor or Pharmacist
If you are taking Ascorbic Acid and your doctor is considering prescribing Fluphenazine (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider