Does Barbituric Acid Derivatives Interact with Acetaminophen Caffeine Dihydrocodeine Bitartrate?
Barbituric Acid Derivatives and Acetaminophen Caffeine Dihydrocodeine Bitartrate have a minor drug interaction according to U.S. FDA drug labeling data. Chronic ingestion of large acetaminophen doses may slightly potentiate anticoagulant effects. The mechanism involves unknown. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Minor
- Acetaminophen Caffeine Dihydrocodeine Bitartrate Class
- Central Nervous System Stimulant
- Management
- Generally manageable
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Barbituric Acid Derivatives and Acetaminophen Caffeine Dihydrocodeine Bitartrate occurs because unknown. Clinically, this means chronic ingestion of large acetaminophen doses may slightly potentiate anticoagulant effects. This is classified as a minor interaction with generally low clinical significance, though your healthcare provider should still be informed that you are taking both medications.
What To Tell Your Doctor or Pharmacist
If you are taking Barbituric Acid Derivatives and your doctor is considering prescribing Acetaminophen Caffeine Dihydrocodeine Bitartrate (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Never stop or change either medication without first consulting your healthcare provider