Bempedoic Acid + Simvastatin Interaction
Majorinteraction on record
Description
Clinically Important Drug Interactions with NEXLETOL Simvastatin Clinical Impact: Concomitant use of NEXLETOL with simvastatin causes an increase in simvastatin concentration and may increase the risk of simvastatin-related myopathy [see Clinical Pharmacology (12.3) ] . Intervention : Avoid concomitant use of NEXLETOL with simvastatin greater than 20 mg. Simvastatin: Avoid concomitant use of NEXLETOL with simvastatin greater than 20 mg.
Source: FDA drug label - bempedoic acid