Does Bempedoic Acid And Ezetimibe Interact with Fenofibrate?
CDI records a moderate classification for Bempedoic Acid And Ezetimibe and Fenofibrate. The stored summary is: Both fenofibrate and ezetimibe may increase cholesterol excretion into bile, leading to cholelithiasis. Monitor for cholelithiasis; consider gallbladder studies if suspected. The mechanism involves increased cholesterol excretion into bile. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
Evidence status
A current label comparison is not yet available for this record. The summary and severity are stored CDI information; they have not been independently validated on this page against the exact product label.
Confirm the medicine, formulation, route, and applicable warning with your pharmacist or prescriber. Independent clinical review has not been recorded.
Saved label reference on DailyMed. This identifier has not been checked here as support for the current claim.
- Stored CDI classification
- Moderate
- Bempedoic Acid And Ezetimibe Class
- Adenosine Triphosphate-Citrate Lyase Inhibitor
- Fenofibrate Class
- Peroxisome Proliferator Receptor alpha Agonist
- Management
- Confirm exact products with your pharmacist
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Increased cholesterol excretion into bile
What To Tell Your Doctor or Pharmacist
If you are taking Bempedoic Acid And Ezetimibe and your doctor is considering prescribing Fenofibrate (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider