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Does Benzoyl Peroxide Interact with Dapsone?

CDI records a minor classification for Benzoyl Peroxide and Dapsone. The stored summary is: Topical co-application may result in temporary local yellow or orange skin discoloration and discoloration of facial hair, resolving within 4-57 days. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.

Severity
Minor
Dapsone Class
Sulfone
Management
Generally manageable
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Benzoyl Peroxide and your doctor is considering prescribing Dapsone (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Benzoyl Peroxide(Fostex)+💊 Dapsone(Aczone)

Severity & Interaction Details

✅
minor
Minor classification in CDI
This classification is not an individual safety assessment. Ask your pharmacist how the record applies to your medications.
Severity scale
MinorContra
On record
Yes
Drug A class
—
Drug B class
Sulfone
Source
NLP:dapsone

What this means in plain English

Topical co-application may result in temporary local yellow or orange skin discoloration and discoloration of facial hair, resolving within 4-57 days.

About Benzoyl Peroxide and Dapsone

Dapsone is a Sulfone. You may recognize them by the brand names Fostex and Aczone.

Source and Limitations

This record was produced by automated extraction from drug-label information, including AI processing. The summary and mechanism are not verbatim FDA quotations. The drug profiles below may describe different formulations from the source label. Confirm the exact product and route with your pharmacist. This page does not establish independent clinical review.

📖 Source: NLP:dapsone

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How this information is prepared: CDI uses automated extraction, including AI, to summarize drug labeling from openFDA and includes separately identified curated-reference records. RxNorm helps identify medications; it does not verify interaction claims. Extracted summaries and CDI severity classifications can contain errors and are not verbatim FDA statements or independent clinical review. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.

CDI: source-linked explanations