Does Bile Acid Binding Resins Interact with Elafibranor?
CDI records a moderate classification for Bile Acid Binding Resins and Elafibranor. The stored summary is: Bile acid sequestrants may reduce ELAFIBRANOR absorption and systemic exposure, decreasing efficacy. The mechanism involves interference with absorption and systemic exposure. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Elafibranor Class
- Peroxisome Proliferator-activated Receptor Agonist
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Interference with absorption and systemic exposure
What To Tell Your Doctor or Pharmacist
If you are taking Bile Acid Binding Resins and your doctor is considering prescribing Elafibranor (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider