Home›Brimonidine Tartrate Ophthalmic Solution 015›Brimonidine Tartrate Ophthalmic Solution 015 + Monoamine Oxidase Inhibitors Maois

Does Brimonidine Tartrate Ophthalmic Solution 015 Interact with Monoamine Oxidase Inhibitors Maois?

Brimonidine Tartrate Ophthalmic Solution 015 and Monoamine Oxidase Inhibitors Maois have a moderate drug interaction according to U.S. FDA drug labeling data. May interfere with brimonidine metabolism and potentially result in increased hypotension and systemic side effects; caution is advised. The mechanism involves interference with amine metabolism and uptake. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Moderate
Management
Monitor for effects
Data Source
U.S. FDA via OpenFDA

How This Interaction Works

The interaction between Brimonidine Tartrate Ophthalmic Solution 015 and Monoamine Oxidase Inhibitors Maois occurs because interference with amine metabolism and uptake. Clinically, this means may interfere with brimonidine metabolism and potentially result in increased hypotension and systemic side effects; caution is advised. This is classified as a moderate interaction. While it may not require stopping either medication, your healthcare provider should be aware you are taking both so they can monitor for potential effects and adjust treatment if necessary.

What To Tell Your Doctor or Pharmacist

If you are taking Brimonidine Tartrate Ophthalmic Solution 015 and your doctor is considering prescribing Monoamine Oxidase Inhibitors Maois (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask whether any dosage adjustments are needed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Brimonidine Tartrate Ophthalmic Solution 015(Brimonidine Tartrate Ophthalmic Solution, 0.15%)+💊 Monoamine Oxidase Inhibitors Maois

Severity & Interaction Details

🟡
moderate
Be aware — moderate interaction
Documented interaction with manageable risk. May require dose adjustment or monitoring.
Severity scale
MinorContra
On record
Yes
Drug A class
—
Drug B class
—
Source
NLP:brimonidine tartrate ophthalmic solution, 0.15%

What this means in plain English

May interfere with brimonidine metabolism and potentially result in increased hypotension and systemic side effects; caution is advised.

What the FDA label says

"Interference with amine metabolism and uptake"

📖 Source: NLP:brimonidine tartrate ophthalmic solution, 0.15%

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Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.