Does Candesartan Cilexetil And Hydrochlorothiazide Interact with Insulin Degludec And Liraglutide?
Candesartan Cilexetil And Hydrochlorothiazide and Insulin Degludec And Liraglutide have a moderate drug interaction according to U.S. FDA drug labeling data. Dosage adjustment of the antidiabetic drug may be required. The mechanism involves hydrochlorothiazide may elevate blood glucose. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Candesartan Cilexetil And Hydrochlorothiazide Class
- Thiazide Diuretic
- Insulin Degludec And Liraglutide Class
- Insulin Analog
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Candesartan Cilexetil And Hydrochlorothiazide and Insulin Degludec And Liraglutide occurs because hydrochlorothiazide may elevate blood glucose. Clinically, this means dosage adjustment of the antidiabetic drug may be required. This is classified as a moderate interaction. While it may not require stopping either medication, your healthcare provider should be aware you are taking both so they can monitor for potential effects and adjust treatment if necessary.
What To Tell Your Doctor or Pharmacist
If you are taking Candesartan Cilexetil And Hydrochlorothiazide and your doctor is considering prescribing Insulin Degludec And Liraglutide (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider