Does Colchicine Tablets 05 Mg Interact with Clarithromycin?
CDI records a contraindicated classification for Colchicine Tablets 05 Mg and Clarithromycin. The stored summary is: Strong CYP3A4 inhibitor causing significant increases in colchicine plasma levels. The mechanism involves cyp3a4 inhibition. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Contraindicated
- Colchicine Tablets 05 Mg Class
- Alkaloid
- Clarithromycin Class
- Macrolide Antimicrobial
- Management
- Do not take together
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
CYP3A4 inhibition
What To Tell Your Doctor or Pharmacist
If you are taking Colchicine Tablets 05 Mg and your doctor is considering prescribing Clarithromycin (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask about alternative medications that do not interact with your current regimen
- Ask how frequently you should be monitored while these are co-prescribed
- Never stop or change either medication without first consulting your healthcare provider