Cyp3a Inducers + Lorlatinib Interaction

Contraindicatedinteraction on record

Description

Strong CYP3A inducers are contraindicated with lorlatinib. Concomitant use decreases lorlatinib plasma concentrations, which may decrease efficacy.

Mechanism

CYP3A induction decreases lorlatinib metabolism

Source: NLP:lorlatinib

Related drug profiles

All Cyp3a Inducers interactions →All Lorlatinib interactions →
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