Drugs Known To Induce Hyperkalemia + Sulfamethoxazole And Trimethoprim Interaction
Majorinteraction on record
Description
Concomitant use with trimethoprim and drugs that induce hyperkalemia may cause hyperkalemia, particularly in patients with renal insufficiency or underlying potassium metabolism disorders.
Mechanism
Trimethoprim induces progressive increase in serum potassium concentrations; additive effect with other hyperkalemia-inducing agents
Source: NLP:sulfamethoxazole and trimethoprim