Home›Drugs That Prolong Qtc Interval›Drugs That Prolong Qtc Interval + Ivosidenib

Does Drugs That Prolong Qtc Interval Interact with Ivosidenib?

Drugs That Prolong Qtc Interval and Ivosidenib have a contraindicated drug interaction according to U.S. FDA drug labeling data. Co-administration may increase risk of QTc interval prolongation. Avoid concomitant use; if unavoidable, monitor closely for QTc prolongation. The mechanism involves additive risk of qtc interval prolongation. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Contraindicated
Ivosidenib Class
Isocitrate Dehydrogenase 1 Inhibitor
Management
Do not take together
Data Source
U.S. FDA via OpenFDA

How This Interaction Works

The interaction between Drugs That Prolong Qtc Interval and Ivosidenib occurs because additive risk of qtc interval prolongation. Clinically, this means co-administration may increase risk of qtc interval prolongation. avoid concomitant use; if unavoidable, monitor closely for qtc prolongation. Because of the severity of this interaction, these medications are contraindicated — meaning they should not be taken together under any circumstances. If you are currently taking both, contact your healthcare provider immediately to discuss alternatives.

What To Tell Your Doctor or Pharmacist

If you are taking Drugs That Prolong Qtc Interval and your doctor is considering prescribing Ivosidenib (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask about alternative medications that do not interact with your current regimen
  • Ask how frequently you should be monitored while these are co-prescribed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Drugs That Prolong Qtc Interval+💊 Ivosidenib

Severity & Interaction Details

⛔
contraindicated
Avoid this combination
FDA labeling lists this pair as contraindicated. The risk outweighs the benefit in nearly all cases.
Severity scale
MinorContra
On record
Yes
Drug A class
—
Drug B class
Isocitrate Dehydrogenase 1 Inhibitor
Source
NLP:ivosidenib

What this means in plain English

Co-administration may increase risk of QTc interval prolongation. Avoid concomitant use; if unavoidable, monitor closely for QTc prolongation.

What the FDA label says

"Additive risk of QTc interval prolongation"

📖 Source: NLP:ivosidenib

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Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.