Drugs That Prolong Qtc Interval has 32 known drug interactions based on U.S. FDA drug labeling data. Of these, 5 are contraindicated combinations that should be avoided entirely. 17 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Adagrasib, Ivosidenib, Ziprasidone. Patients taking Drugs That Prolong Qtc Interval should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 32
- Contraindicated
- 5
- Major
- 17
- Moderate
- 7
Contraindicated (5)
- Drugs That Prolong Qtc Interval + Adagrasib— Concomitant use with KRAZATI is contraindicated.
- Drugs That Prolong Qtc Interval + Ivosidenib— Co-administration may increase risk of QTc interval prolongation. Avoid concomitant use; if unavoidable, monitor closely…
- Drugs That Prolong Qtc Interval + Ziprasidone— Ziprasidone should not be used in combination with other drugs that have demonstrated QT prolongation due to risk of ser…
- Drugs That Prolong Qtc Interval + Ziprasidone Hcl— Ziprasidone should not be used in combination with other drugs that have demonstrated QT prolongation due to risk of ser…
- Drugs That Prolong Qtc Interval + Ziprasidone Mesylate— Ziprasidone should not be used in combination with other drugs that have demonstrated QT prolongation due to risk of ser…
Major (17)
- Drugs That Prolong Qtc Interval + Aclidinium Bromide And Formoterol Fumarate— Increased risk of ventricular arrhythmias when used with beta-2 agonists. Use with caution.
- Drugs That Prolong Qtc Interval + Arformoterol Tartrate— Drugs that prolong QTc interval may potentiate cardiovascular effects. Use with extreme caution.
- Drugs That Prolong Qtc Interval + Bedaquiline Fumarate— Additional QTc interval prolongation observed during combination treatment with SIRTURO. Monitor ECGs and discontinue if…
- Drugs That Prolong Qtc Interval + Citalopram— Concomitant use can cause additional QT prolongation.
- Drugs That Prolong Qtc Interval + Formoterol Fumarate— May potentiate cardiovascular effects of formoterol with increased risk of ventricular arrhythmias. Use with extreme cau…
- Drugs That Prolong Qtc Interval + Formoterol Fumarate Dihydrate— May potentiate cardiovascular effects and increase risk of ventricular arrhythmias. Use with extreme caution.
- Drugs That Prolong Qtc Interval + Glasdegib— Co-administration may increase risk of QTc interval prolongation. Avoid concomitant use or monitor closely if unavoidabl…
- Drugs That Prolong Qtc Interval + Glycopyrrolate And Formoterol Fumarate— Use with extreme caution. May potentiate cardiovascular effects and increase risk of ventricular arrhythmias.
- Drugs That Prolong Qtc Interval + Haloperidol Decanoate— Concomitant use may result in greater QTc interval prolongation and adverse reactions including torsade de pointes, seri…
- Drugs That Prolong Qtc Interval + Hydroxychloroquine Sulfate— Increased risk of inducing ventricular arrhythmias when used concomitantly with hydroxychloroquine sulfate tablets.
- Drugs That Prolong Qtc Interval + Letrozole And Ribociclib— Coadministration with drugs known to prolong QT interval should be avoided due to risk of QT prolongation. If unavoidabl…
- Drugs That Prolong Qtc Interval + Lonafarnib— Avoid concomitant use. Lonafarnib causes QTc prolongation; combined use may result in greater QTc interval increase and …
- Drugs That Prolong Qtc Interval + Olodaterol Respimat Inhalation Spray— May potentiate cardiovascular effects of olodaterol and increase risk of ventricular arrhythmias. Use with extreme cauti…
- Drugs That Prolong Qtc Interval + Oxaliplatin— QT interval prolongation and ventricular arrhythmias can occur with coadministration. Avoid coadministration of oxalipla…
- Drugs That Prolong Qtc Interval + Pitolisant Hydrochloride— Concomitant use may add to QT effects and increase risk of cardiac arrhythmia. Avoid combination.
- Drugs That Prolong Qtc Interval + Revumenib— Concomitant use should be avoided as it may result in increased QTc interval and associated adverse reactions. If unavoi…
- Drugs That Prolong Qtc Interval + Tiotropium Bromide And Olodaterol— QTc-prolonging drugs may potentiate cardiovascular effects and increase risk of ventricular arrhythmias. Use with extrem…
Moderate (7)
- Drugs That Prolong Qtc Interval + Cabotegravir And Rilpivirine— CABENUVA should be used with caution in combination with drugs with a known risk of Torsade de Pointes due to rilpivirin…
- Drugs That Prolong Qtc Interval + Emtricitabine, Rilpivirine Hydrochloride, And Tenofovir Alafenamide— Limited information on potential pharmacodynamic interaction; higher RPV doses prolonged QTc interval. Consider alternat…
- Drugs That Prolong Qtc Interval + Entrectinib— QTc interval prolongation can occur with ROZLYTREK. Avoid coadministration with other products with known potential to p…
- Drugs That Prolong Qtc Interval + Granisetron Hydrochloride— Concurrent use of granisetron oral solution with drugs known to prolong QT interval and/or are arrhythmogenic may result…
- Drugs That Prolong Qtc Interval + Olanzapine And Fuoxetine— Use olanzapine and fluoxetine with caution with other QT-prolonging drugs.
- Drugs That Prolong Qtc Interval + Pasireotide— Co-administration may have additive effects on QT interval prolongation; monitoring of QT interval effects at 21 days is…
- Drugs That Prolong Qtc Interval + Sunitinib Malate— Sunitinib is associated with QTc interval prolongation. Monitor QT interval more frequently with concomitant QT-prolongi…