Does Elagolix And Estradiol And Norethisterone Interact with Midazolam?
CDI records a moderate classification for Elagolix And Estradiol And Norethisterone and Midazolam. The stored summary is: ORIAHNN may decrease midazolam plasma concentrations. Consider increasing midazolam dose by no more than 2-fold and individualize therapy based on patient response. The mechanism involves cyp3a induction. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Midazolam Class
- Benzodiazepine
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
CYP3A induction
What To Tell Your Doctor or Pharmacist
If you are taking Elagolix And Estradiol And Norethisterone and your doctor is considering prescribing Midazolam (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider