Does Elagolix And Estradiol And Norethisterone Interact with Mao Inhibitors?
CDI records a contraindicated classification for Elagolix And Estradiol And Norethisterone and Mao Inhibitors. The stored summary is: OATP1B1 inhibitors that significantly increase elagolix plasma concentrations are contraindicated due to increased risk of elagolix-associated adverse reactions. The mechanism involves oatp1b1 inhibition. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Contraindicated
- Management
- Do not take together
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
OATP1B1 inhibition
What To Tell Your Doctor or Pharmacist
If you are taking Elagolix And Estradiol And Norethisterone and your doctor is considering prescribing Mao Inhibitors (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask about alternative medications that do not interact with your current regimen
- Ask how frequently you should be monitored while these are co-prescribed
- Never stop or change either medication without first consulting your healthcare provider