Does Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen Interact with Drugs That Prolong Qtc Interval?
Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen and Drugs That Prolong Qtc Interval have a moderate drug interaction according to U.S. FDA drug labeling data. Limited information on potential pharmacodynamic interaction; higher RPV doses prolonged QTc interval. Consider alternative medications in patients taking drugs with known Torsade de Pointes risk. The mechanism involves higher than recommended rpv doses prolong qtc interval. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen Class
- Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen and Drugs That Prolong Qtc Interval occurs because higher than recommended rpv doses prolong qtc interval. Clinically, this means limited information on potential pharmacodynamic interaction; higher rpv doses prolonged qtc interval. consider alternative medications in patients taking drugs with known torsade de pointes risk. This is classified as a moderate interaction. While it may not require stopping either medication, your healthcare provider should be aware you are taking both so they can monitor for potential effects and adjust treatment if necessary.
What To Tell Your Doctor or Pharmacist
If you are taking Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen and your doctor is considering prescribing Drugs That Prolong Qtc Interval (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider