Ethinyl Estradiol + Fluconazole Interaction

Moderateinteraction on record

Description

Fluconazole 200 mg increased ethinyl estradiol AUC by 38% and fluconazole 300 mg increased it by 24%. Fluconazole 50 mg showed no significant effect.

Mechanism

Inhibition of ethinyl estradiol metabolism

Source: NLP:fluconazole