Grapefruit Juice + Propafenone Hydrochloride Interaction

Contraindicatedinteraction on record

Description

CYP3A4 inhibitor; simultaneous use with both CYP2D6 and CYP3A4 inhibitors should be avoided due to increased risk of proarrhythmia.

Mechanism

CYP3A4 inhibition

Source: NLP:propafenone hydrochloride