Does Hepatitis B Immune Globulin Human Interact with Measles Vaccine?
Hepatitis B Immune Globulin Human and Measles Vaccine have a moderate drug interaction according to U.S. FDA drug labeling data. Live virus vaccines should be deferred until approximately three months after administration of Hepatitis B Immune Globulin. Revaccination may be necessary if given shortly after live virus vaccination. The mechanism involves immune globulin may interfere with live vaccine effectiveness. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Hepatitis B Immune Globulin Human Class
- Human Immunoglobulin
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Hepatitis B Immune Globulin Human and Measles Vaccine occurs because immune globulin may interfere with live vaccine effectiveness. Clinically, this means live virus vaccines should be deferred until approximately three months after administration of hepatitis b immune globulin. revaccination may be necessary if given shortly after live virus vaccination. This is classified as a moderate interaction. While it may not require stopping either medication, your healthcare provider should be aware you are taking both so they can monitor for potential effects and adjust treatment if necessary.
What To Tell Your Doctor or Pharmacist
If you are taking Hepatitis B Immune Globulin Human and your doctor is considering prescribing Measles Vaccine (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider