Does Human Immunoglobulin G Interact with Mumps Vaccine?
CDI records a moderate classification for Human Immunoglobulin G and Mumps Vaccine. The stored summary is: Immunoglobulin may transiently impair efficacy of live attenuated mumps vaccine due to interference with active antibody response from passively acquired antibodies. The mechanism involves passive antibodies interfere with active immune response to live vaccine. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Human Immunoglobulin G Class
- Human Immunoglobulin G
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Passive antibodies interfere with active immune response to live vaccine
What To Tell Your Doctor or Pharmacist
If you are taking Human Immunoglobulin G and your doctor is considering prescribing Mumps Vaccine (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider