HomeImipenem And CilastatinImipenem And Cilastatin + Valganciclovir Hydrochloride

Does Imipenem And Cilastatin Interact with Valganciclovir Hydrochloride?

Imipenem And Cilastatin and Valganciclovir Hydrochloride have a contraindicated drug interaction according to U.S. FDA drug labeling data. Generalized seizures have been reported in patients receiving ganciclovir and imipenem-cilastatin. Coadministration is not recommended. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Contraindicated
Imipenem And Cilastatin Class
Penem Antibacterial
Management
Do not take together
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Imipenem And Cilastatin and your doctor is considering prescribing Valganciclovir Hydrochloride (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask about alternative medications that do not interact with your current regimen
  • Ask how frequently you should be monitored while these are co-prescribed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Imipenem And Cilastatin(Imipenem And Cilastatin)+💊 Valganciclovir Hydrochloride(Valganciclovir Hydrochloride For Oral)

Severity & Interaction Details

contraindicated
Avoid this combination
FDA labeling lists this pair as contraindicated. The risk outweighs the benefit in nearly all cases.
Severity scale
MinorContra
On record
Yes
Drug A class
Penem Antibacterial
Drug B class
Source
NLP:valganciclovir hydrochloride

What this means in plain English

Generalized seizures have been reported in patients receiving ganciclovir and imipenem-cilastatin. Coadministration is not recommended.

Share this result:XFacebookWhatsAppReddit
Add more drugs
Check Imipenem And Cilastatin and Valganciclovir Hydrochloride against your full medication list

Most patients take more than two medications. CDI checks every pair across up to 20 drugs simultaneously — including OTCs and common supplements.

Add more drugs →

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.