Ixabepilone + Cyp3a Inducers Interaction
Majorinteraction on record
Description
Coadministration decreases ixabepilone plasma concentration, potentially decreasing efficacy. Avoid if possible; if unavoidable, increase IXEMPRA dose.
Mechanism
CYP3A4 induction decreases ixabepilone plasma concentration
Source: NLP:ixabepilone