HomeLedipasvir And SofosbuvirLedipasvir And Sofosbuvir + Omeprazole

Does Ledipasvir And Sofosbuvir Interact with Omeprazole?

Ledipasvir And Sofosbuvir and Omeprazole have a unknown drug interaction according to U.S. FDA drug labeling data. Proton-pump inhibitors (e.g., omeprazole) Proton-pump inhibitor doses comparable to omeprazole 20 mg or lower can be administered simultaneously with HARVONI under fasted conditions. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Unknown
Ledipasvir And Sofosbuvir Class
Hepatitis C Virus NS5A Inhibitor
Omeprazole Class
Proton Pump Inhibitor
Management
Consult your pharmacist
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Ledipasvir And Sofosbuvir and your doctor is considering prescribing Omeprazole (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Ledipasvir And Sofosbuvir(Ledipasvir And Sofosbuvir)+💊 Omeprazole

Severity & Interaction Details

ℹ️
unknown
Interaction documented — severity unclassified
The FDA label notes an interaction but the severity is not classified in our dataset.
Severity scale
MinorContra
On record
Yes
Drug A class
Hepatitis C Virus NS5A Inhibitor
Drug B class
Proton Pump Inhibitor
Source
FDA drug label - ledipasvir and sofosbuvir

What this means in plain English

Proton-pump inhibitors (e.g., omeprazole) Proton-pump inhibitor doses comparable to omeprazole 20 mg or lower can be administered simultaneously with HARVONI under fasted conditions.

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Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.