Does Macimorelin Acetate Interact with Clonidine?
CDI records a moderate classification for Macimorelin Acetate and Clonidine. The stored summary is: May transiently elevate growth hormone concentrations and impact accuracy of MACRILEN diagnostic test. Avoid concomitant use. The mechanism involves transient growth hormone elevation. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Macimorelin Acetate Class
- Growth Hormone Secretagogue Receptor Agonist
- Clonidine Class
- Central alpha-2 Adrenergic Agonist
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Transient growth hormone elevation
What To Tell Your Doctor or Pharmacist
If you are taking Macimorelin Acetate and your doctor is considering prescribing Clonidine (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider