Mao Inhibitors + Daptomycin Interaction
Moderateinteraction on record
Description
May increase risk of myopathy with elevated CPK levels when used concomitantly. Consider temporarily suspending HMG-CoA reductase inhibitors in patients receiving daptomycin.
Mechanism
HMG-CoA reductase inhibitors may cause myopathy manifested as muscle pain or weakness with elevated creatine phosphokinase
Source: NLP:daptomycin