Mao Inhibitors + Diclofenac Sodium Interaction

Majorinteraction on record

Description

May result in deterioration of renal function including possible acute renal failure in elderly, volume-depleted, or renally impaired patients. NSAIDs may diminish antihypertensive effect.

Mechanism

Reduced renal function; diminished antihypertensive effect

Source: NLP:diclofenac sodium