Mao Inhibitors + Imlunestrant Interaction
Majorinteraction on record
Description
Concomitant use increases imlunestrant exposure, which may increase the risk of adverse reactions. Avoid concomitant use; if unavoidable, reduce imlunestrant dosage.
Mechanism
Imlunestrant is a CYP3A substrate; strong CYP3A inhibitors increase its exposure
Source: NLP:imlunestrant