Mao Inhibitors + Telmisartan And Hydrochlorothiazide Interaction
Majorinteraction on record
Description
COX-2 inhibitors may result in deterioration of renal function and reduce the diuretic, natriuretic, and antihypertensive effects similar to NSAIDs.
Mechanism
COX-2 inhibitors antagonize effects of ARBs and diuretics; renal impairment risk in susceptible patients
Source: NLP:telmisartan and hydrochlorothiazide