HomeMetoprolol Tartrate And HydrochlorothiazideMetoprolol Tartrate And Hydrochlorothiazide + Hydrochlorothiazide

Does Metoprolol Tartrate And Hydrochlorothiazide Interact with Hydrochlorothiazide?

Metoprolol Tartrate And Hydrochlorothiazide and Hydrochlorothiazide have a unknown drug interaction according to U.S. FDA drug labeling data. 7.2 Drug Interactions with Hydrochlorothiazide Antidiabetic Drugs (oral agents and insulin) Dosage adjustment of the antidiabetic drug may be required. Ion Exchange Resins Absorption of hydrochlorothiazide is impaired in the presence of anionic exchange resins. Single doses of either cholestyramine or colestipol resins bind the hydrochlorothiazide and reduce its absorption from the gastrointestinal tract by up to 85% and 43%, respectively. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Unknown
Metoprolol Tartrate And Hydrochlorothiazide Class
Thiazide Diuretic
Hydrochlorothiazide Class
Thiazide Diuretic
Management
Consult your pharmacist
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Metoprolol Tartrate And Hydrochlorothiazide and your doctor is considering prescribing Hydrochlorothiazide (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Metoprolol Tartrate And Hydrochlorothiazide(Metoprolol Tartrate And Hydrochlorothiazide)+💊 Hydrochlorothiazide

Severity & Interaction Details

ℹ️
unknown
Interaction documented — severity unclassified
The FDA label notes an interaction but the severity is not classified in our dataset.
Severity scale
MinorContra
On record
Yes
Drug A class
Thiazide Diuretic
Drug B class
Thiazide Diuretic
Source
FDA drug label - metoprolol tartrate and hydrochlorothiazide

What this means in plain English

7.2 Drug Interactions with Hydrochlorothiazide Antidiabetic Drugs (oral agents and insulin) Dosage adjustment of the antidiabetic drug may be required. Ion Exchange Resins Absorption of hydrochlorothiazide is impaired in the presence of anionic exchange resins. Single doses of either cholestyramine or colestipol resins bind the hydrochlorothiazide and reduce its absorption from the gastrointestinal tract by up to 85% and 43%, respectively.

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Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.