Does Monoamine Oxidase Inhibitors Maois Interact with Butalbital And Acetaminophen?
Monoamine Oxidase Inhibitors Maois and Butalbital And Acetaminophen have a moderate drug interaction according to U.S. FDA drug labeling data. MAO inhibitors may enhance the CNS effects of butalbital. The mechanism involves cns effect enhancement. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Butalbital And Acetaminophen Class
- Barbiturate
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Monoamine Oxidase Inhibitors Maois and Butalbital And Acetaminophen occurs because cns effect enhancement. Clinically, this means mao inhibitors may enhance the cns effects of butalbital. This is classified as a moderate interaction. While it may not require stopping either medication, your healthcare provider should be aware you are taking both so they can monitor for potential effects and adjust treatment if necessary.
What To Tell Your Doctor or Pharmacist
If you are taking Monoamine Oxidase Inhibitors Maois and your doctor is considering prescribing Butalbital And Acetaminophen (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider