Nonselective Beta Adrenergic Antagonists + Articaine Hydrochloride And Epinephrine Bitartrate Interaction

Majorinteraction on record

Description

May produce severe, prolonged hypertension when local anesthetic solutions containing epinephrine are administered to patients receiving these agents.

Mechanism

Epinephrine interaction with beta-adrenergic blockade

Source: NLP:articaine hydrochloride, epinephrine bitartrate