Nonselective Beta Adrenergic Antagonists + Propylthiouracil Interaction

Moderateinteraction on record

Description

Hyperthyroidism increases clearance of beta blockers. A reduced dose may be needed when hyperthyroid patients become euthyroid with propylthiouracil treatment.

Mechanism

Increased clearance of beta blockers with high extraction ratio in hyperthyroid state

Source: NLP:propylthiouracil