Does Nonsteroidal Anti Inflammatory Drugs Nsaids Interact with Zoledronic Acid?
CDI records a moderate classification for Nonsteroidal Anti Inflammatory Drugs Nsaids and Zoledronic Acid. The stored summary is: Potentially nephrotoxic drugs; caution indicated when used with zoledronic acid due to increased risk of renal impairment. The mechanism involves additive nephrotoxicity. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Additive nephrotoxicity
What To Tell Your Doctor or Pharmacist
If you are taking Nonsteroidal Anti Inflammatory Drugs Nsaids and your doctor is considering prescribing Zoledronic Acid (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider