Nsaids + Azilsartan Kamedoxomil Interaction
Majorinteraction on record
Description
NSAIDs increase risk of renal dysfunction and acute renal failure when combined with azilsartan, particularly in elderly, volume-depleted, or renally impaired patients. NSAIDs also attenuate antihypertensive effect.
Mechanism
Deterioration of renal function; interference with antihypertensive effect
Source: NLP:azilsartan kamedoxomil and chlorthalidone