Nsaids + Irbesartan And Hydrochlorothiazide Interaction
Majorinteraction on record
Description
NSAIDs can reduce diuretic and natriuretic effects, and may lead to renal impairment and reduced antihypertensive effect. Monitor renal function periodically.
Mechanism
Reduction of diuretic and natriuretic effects
Source: NLP:irbesartan and hydrochlorothiazide