Nsaids + Olmesartan Medoxomil Hydrochlorothiazide Interaction
Majorinteraction on record
Description
Co-administration may result in deterioration of renal function, including possible acute renal failure, and may attenuate antihypertensive effects. Monitor renal function and blood pressure.
Mechanism
NSAIDs impair renal function when combined with angiotensin II receptor antagonists and reduce diuretic and antihypertensive effects of thiazides
Source: NLP:olmesartan medoxomil-hydrochlorothiazide