Oral Contraceptives + Modafinil Interaction
Moderateinteraction on record
Description
Effectiveness of steroidal contraceptives may be reduced when used with modafinil. Alternative or concomitant contraception methods recommended during treatment and for one month after discontinuation.
Mechanism
Induction of CYP3A4/5 metabolic enzymes increasing clearance
Source: NLP:modafinil