Other Anticholinergic Agents + Pentazocine Hydrochloride And Naloxone Hydrochloride Interaction
Majorinteraction on record
Description
Concomitant use increases risk of hypotension, respiratory depression, profound sedation, coma, and death due to additive CNS depressant effects.
Mechanism
Additive pharmacologic effect on CNS depression
Source: NLP:pentazocine and naloxone