P Gp Or Bcrp Substrates + Imlunestrant Interaction
Majorinteraction on record
Description
Imlunestrant inhibits P-gp and BCRP, increasing substrate exposure and risk of adverse reactions. Avoid concomitant use unless minimal concentration changes are acceptable.
Mechanism
Imlunestrant inhibits P-gp and BCRP transporters
Source: NLP:imlunestrant