P Gp Or Bcrp Substrates + Mavorixafor Interaction

Moderateinteraction on record

Description

Increase mavorixafor Cmax and AUC. Monitor for adverse reactions and reduce dosage by 100 mg steps if necessary, but not below 200 mg.

Mechanism

Inhibition of P-glycoprotein-mediated efflux of mavorixafor

Source: NLP:mavorixafor