Pentazocine Hydrochloride And Naloxone Hydrochloride + Other Anticholinergic Agents Interaction
Majorinteraction on record
Description
Concomitant use increases risk of hypotension, respiratory depression, profound sedation, coma, and death due to additive CNS depressant effects.
Mechanism
Additive pharmacologic effect on CNS depression
Source: NLP:pentazocine and naloxone