HomePhenylephrine HciPhenylephrine Hci + Tranylcypromine Sulfate

Does Phenylephrine Hci Interact with Tranylcypromine Sulfate?

Phenylephrine Hci and Tranylcypromine Sulfate have a contraindicated drug interaction according to U.S. FDA drug labeling data. Sympathomimetic vasopressor contraindicated; avoid or emergency use only with tranylcypromine discontinuation and monitoring. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Contraindicated
Management
Do not take together
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Phenylephrine Hci and your doctor is considering prescribing Tranylcypromine Sulfate (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask about alternative medications that do not interact with your current regimen
  • Ask how frequently you should be monitored while these are co-prescribed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Phenylephrine Hci(Phenylephrine Hci)+💊 Tranylcypromine Sulfate(Tranylcypromine Sulfate)

Severity & Interaction Details

contraindicated
Avoid this combination
FDA labeling lists this pair as contraindicated. The risk outweighs the benefit in nearly all cases.
Severity scale
MinorContra
On record
Yes
Drug A class
Drug B class
Source
NLP:tranylcypromine sulfate

What this means in plain English

Sympathomimetic vasopressor contraindicated; avoid or emergency use only with tranylcypromine discontinuation and monitoring.

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Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.